APOE anticorps (Agarose Beads)

N° du produit ABIN7795847

Cet anticorps Chèvre Polyclonal détecte spécifiquement APOE dans . Il présente une réactivité envers Humain.

Aperçu rapide pour APOE anticorps (Agarose Beads) (ABIN7795847)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp APOE est non-conjugé

Application: Veuillez nous consulter SVP

Clone: G05

Détail du produit anti-APOE anticorps

Épitope: Agarose Beads

Fonction: Goat anti-Human ApoE Antibody Agarose Immobilized

Purification: Purified

Immunogène: Human Apolipoprotein E

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 5 mg/mL

Buffer: 75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, 0.1 mM PMSF, pH 7.3

Agent conservateur: Other preservative, PMSF, Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: ApoE

Sujet: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

ID gène: 348

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism